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“The purpose of the ‘Brains Behind Weight Loss’ campaignis to establish that the brain may play a powerful role for patients who are struggling to lose weight,” said Salma Jutt, Vice President of US Marketing at Orexigen. “Our goal is to motivate patients to ask a health care practitioner about CONTRAVE, which is believed to work on two areas of the brain to reduce hunger and help control cravings. We want to help patients understand why they struggle to lose weight, help alleviate their frustration and encourage them to learn more about how CONTRAVE may help.” The concept was driven by extensive qualitative and quantitative research aimed at patients who were motivated and committed to lose weight. Orexigen learned that patients believe an inability to control cravings is a key reason why their intention to lose weight fails. “Brains Behind Weight Loss” explains how different areas of the brain can cause hunger and cravings, underscoring that diet and exercise alone may not be enough to treat the complexity of weight loss. The initial target is primarily women, as more than 80% of patients being treated are women. linkThe integrated campaign will span network and cable television, magazines, digital displays, online video, social media and a new website. See the TV commercial at www.CONTRAVE.com . About CONTRAVE Indication CONTRAVE is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of: * 30 kg/m2 or greater (obese) or * 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia) Limitations of Use The effect of CONTRAVE on cardiovascular morbidity and mortality has not been established. The safety and effectiveness of CONTRAVE in combination with other products intended for weight loss, including prescription drugs and over-the-counter drugs, and herbal preparations, have not been established.
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